A developmental conundrum

THE CONUNDRUM OF EUTHANASIA

Pervasive developmental disorders. Etiological, diagnostic and treatment conundrum.

Pervasive developmental disorders are severe childhood psychiatric disorders that afflict millions of children worldwide. Despite availability of tremendous data on these disorders, there is a paucity of information among clinicians including mental health professionals. Pervasive developmental disorders, caused by multiple neurobiological and environmental etiologies, are characterized mainly ...

The Conundrum of Online Prescription Drug Promotion; Comment on “Trouble Spots in Online Direct-to-Consumer Prescription Drug Promotion: A Content Analysis of FDA Warning Letters”

This commentary discusses pertinent issues from Hyosun Kim’s paper on online prescription drug promotion. The study is well-designed and the findings highlight some of the consequences of the Food and Drug Administration’s (FDA’s) decision to deregulate online advertising of prescription drugs. While Kim’s findings confirm some of the early concerns, they also provide a perspective of implement...

What serial homologs can tell us about the origin of insect wings

Although the insect wing is a textbook example of morphological novelty, the origin of insect wings remains a mystery and is regarded as a chief conundrum in biology. Centuries of debates have culminated into two prominent hypotheses: the tergal origin hypothesis and the pleural origin hypothesis. However, between these two hypotheses, there is little consensus in regard to the origin tissue of...

Lateral Nasal Wall Respiratory Epithelial Adenomatoid Hamartoma (REAH): A Diagnostic Conundrum

Introduction: This study aims to report a rare case of a respiratory epithelial adenomatoid hamartoma (REAH) of the lateral nasal wall that had initially presented as a fungating mass, similar to that of a sinonasal malignancy, and its complete removal from the lateral nasal wall.   Case Report: We report the case of a 58-year-old woman who presented to us with a chief complaint of recurrent ri...

The Cambrian conundrum: early divergence and later ecological success in the early history of animals.

Diverse bilaterian clades emerged apparently within a few million years during the early Cambrian, and various environmental, developmental, and ecological causes have been proposed to explain this abrupt appearance. A compilation of the patterns of fossil and molecular diversification, comparative developmental data, and information on ecological feeding strategies indicate that the major anim...